ABSTRACT Sand flies are the natural vectors for the Leishmania species that produce a spectrum of diseases in their mammalian hosts, including humans.Studies of sand fly/Leishmania interactions have been limited by the absence of genome editing techniques applicable to these insects.In this report, we adapted CRISPR (clustered regularly interspaced
Abstract Background In the postgenomic era, high throughput protein expression and protein microarray technologies have progressed markedly permitting screening of therapeutic reagents and discovery of novel protein functions.Hexa-histidine is one of the most commonly used fusion tags for protein expression due to its small size and convenient puri
In current modern age of worldwide processes of globalization and globalism a process of desovereigntization of national state and economy has become a general process.Therefore national state has been faced with numerous challenges and it has been in a permanent state of crisis.Within the process of globalization most often rich enclaves of nation
Nutraceutical candy jellies are gaining popularity as a potential approach to deliver antioxidants in a palatable form.This study investigated the antioxidant activity of Cucurbita moschata puree combined with Averrhoa carambola juice, formulated into jelly candies.Design-Expert software V.13 was used to optimize the jelly candy base formula.The co
Gene transfer of drug resistance (CTX-R) genes can be used to protect the hematopoietic system socialstudiesscholar.com from the toxicity of anticancer chemotherapy and this concept recently has been proven by overexpression of a mutant O6-methylguaninemethyltransferase in the hematopoietic system of glioblastoma patients treated with temozolomide.